Evaluation of hepatoprotective activity of Haldinia cordifolia against paracetamol induced liver damage in rats
نویسنده
چکیده
Hepatoprotective activity of ethanol extract of Haldinia cordifolia against paracetamol induced hepatic damage in albino rats was observed. In the present study the effect of ethanol extract of Haldinia cordifolia on serum markers such as SGPT, SGOT, ALP and Serum total bilirubin, anti oxidant studies such as SOD, CAT and LPO and Histopathological studies have been studied to find out the possible mechanism of hepatoprotection. It was observed that extracts of Haldinia cordifolia has reversal effects on the levels of above mentioned parameters in paracetamol hepatotoxicity. The extract of Haldinia cordifolia functions as a hepatoprotective agent and this hepatoprotective activity of Haldinia cordifolia may be due normalization of impaired membrane function activity.
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